Insulin resistance (part 2) - how insulin resistance can be improve (often dramatically) over time.
If insulin resistance has come up for you — whether through blood tests, symptoms, or a quiet sense that something isn’t quite right — you’re not alone. Many women sit in my clinic feeling as though their body has suddenly become more complicated, as if food choices carry more weight than they used to and everyday decisions feel loaded. That can be unsettling, and it’s completely understandable.
I want to reassure you of something important: this isn’t about being perfect or doing everything “right.” It’s about gently reducing how hard your body has to work by lowering unnecessary insulin demand. The truly encouraging news is that insulin sensitivity is not fixed. When the signals you send your body change, your metabolism is very capable of changing with them.
This is part 2 of an insulin resistance series- if you want to read part 1 first -> what is Insulin resistance and how it is tested, click here.
This article is here to support you. It’s intentionally detailed and steady, because most women don’t need another set of rules — they need clarity, practical guidance, and reassurance that meaningful progress is possible without turning their life upside down.
The big picture first: what “reversing” insulin resistance actually means
When insulin resistance improves, several things can start shifting in the background:
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Less insulin is needed to manage the same meals
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Fat clears more easily from the liver and muscle (those “ectopic fat” stores that interfere with signalling)
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Inflammation and cellular stress settle
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Energy and appetite regulation often become steadier
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Blood markers can improve (triglycerides, HDL, liver enzymes, fasting insulin/HOMA-IR, sometimes blood pressure)
Importantly, these improvements can begin before the scales change, and sometimes before “standard” glucose markers move much. In other words: you can be getting metabolically healthier even if it isn’t obvious yet.
Your most powerful levers
There are many helpful strategies, but a few consistently do the “heavy lifting”:
1) Reducing ectopic fat and overall insulin load (often through gentle, sustainable weight loss)
For many women (not all), even a modest reduction in body fat — especially visceral (fat around your organs) and liver fat — meaningfully improves insulin sensitivity. Evidence summaries commonly cite improvements with around 7–10% weight loss, particularly when paired with movement.
This does not mean pursuing extreme dieting. It means creating a pattern that gradually reduces the metabolic “overflow” that drives insulin resistance.
2) Building and using muscle (your best long-term ally)
Muscle is a major “sink” for glucose disposal and a key driver of insulin sensitivity. Both resistance training and aerobic activity help — and the combination tends to work best.
And here’s the bit women often find liberating: a lot of the benefit comes from consistency, not intensity.
3) Meal pattern and meal timing (insulin needs breaks)
Your pancreas isn’t “fragile,” but it does respond to your eating rhythm. Constant grazing keeps insulin elevated more often than necessary. Creating periods where insulin can rise and then fall can be surprisingly helpful.
Some people also benefit from time-structured eating (more on that below), but it should always be adapted to your life, sleep, stress load, and hormonal stage.
4) Sleep and stress (quietly huge)
Poor sleep and chronic stress change glucose handling and increase insulin demand through stress hormones. In lifestyle evidence summaries, sleep regularity and stress-reduction practices show additional benefits on insulin sensitivity and glycaemic control.
Before you change anything: choose the right “starting point”
Most women try to start at the hardest point — and then blame themselves when it doesn’t stick.
A better question is:
“Where is my biggest source of insulin strain right now?”
For many women it’s one (or more) of these:
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a very refined-carb breakfast that spikes hunger mid-morning
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evening eating + tired snacking
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long hours of sitting, even if they exercise
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poor sleep and a wired nervous system
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meals that are carbs on their own, with little fibre/protein
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eating pattern that leaves them too hungry, leading to rebound eating
You don’t need to fix everything. Pick the one that feels most realistic to shift first.
Muscle and movement: what helps most (without the “all or nothing”)
Why movement — especially muscle — is so powerful for insulin sensitivity
When we talk about insulin sensitivity, muscle is one of the most important tissues in the body to understand. Skeletal muscle is the largest insulin-sensitive tissue in the body and the main place glucose is meant to go after a meal. In fact, it’s responsible for the majority of glucose disposal once you eat. The more active, strong, and metabolically healthy your muscle is, the less insulin your body needs to keep blood sugars in a healthy range.
I often explain it like this in clinic: muscle is a glucose “sink.” The more muscle you have, the bigger that sink becomes. Muscle cells are rich in GLUT-4 transporters — the doorways insulin uses to move glucose out of the bloodstream and into the cell. With more muscle, you have more of these doorways available, which means your body can manage blood sugar with less insulin, not more. Over time, this improves insulin sensitivity not just during movement, but even when you’re resting.
Muscle also has a unique advantage: when it contracts, it can pull glucose out of the bloodstream without needing insulin at all. That gives your pancreas a break. Repeated over days and weeks, this lowers circulating insulin levels and makes metabolism more flexible. The opposite is also true — when muscles are underused, insulin resistance develops more easily.
This is why food changes often help you see improvements quite quickly — meals create immediate insulin signals — but muscle is your long-term lever. It quietly reduces insulin demand in the background, day after day, making metabolic health easier to sustain over time.
Rather than thinking of movement as “exercise you have to fit in,” it helps to think in layers — because each layer supports insulin sensitivity in a different way.
Layer 1: Use your muscles often (NEAT + breaking up sitting)
This is the foundation, and it’s far more powerful than most people realise.
Long periods of sitting reduce muscle activity, which means fewer glucose transporters are switched on in muscle cells. Even if you exercise regularly, sitting for most of the day can still impair insulin sensitivity. Quite simply, muscles that aren’t being used stop doing their job as well.
Frequent, low-level movement keeps muscle metabolism switched on throughout the day and lowers the amount of insulin needed to manage everyday meals.
This includes things like:
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standing
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walking
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carrying groceries
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stairs
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gardening
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general household movement
Simple, realistic ways to build this in:
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a 2–5 minute walk every hour or two
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standing or pacing during phone calls
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“movement snacks” (a few squats while the kettle boils, a lap of the house, light stretching)
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a 10-minute walk after dinner most days
These small actions truly add up — and they directly improve how your muscles handle glucose across the day.
Layer 2: Strength and resistance work (2–4 times per week)
This is where muscle becomes a long-term metabolic ally.
Strength training doesn’t just make muscles stronger — it makes them more insulin sensitive. Resistance training increases muscle mass, improves mitochondrial function, and enhances the muscle’s ability to store glucose as glycogen rather than leaving it circulating in the blood.
More muscle means:
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a larger sink for glucose
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more GLUT-4 transporters available for insulin-mediated glucose uptake
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less insulin required per meal
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better blood sugar stability over time — even at rest
Resistance training also reduces visceral fat and fat stored within muscle itself, both of which are strongly linked to insulin resistance. Importantly, it improves insulin sensitivity independent of weight loss, which is why metabolic health often improves before the scale changes.
You don’t need extreme workouts to get these benefits. This can include:
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weights (gym or home)
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resistance bands
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bodyweight exercises
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Pilates-style strength work, if progressively loaded
If you’re starting from scratch, begin with 10–15 minutes, twice a week, and build gradually. Your job is not to exhaust yourself — it’s to send a consistent signal to your body that muscle matters. That signal compounds over time.
There is one gentle reality check I always share: building meaningful muscle takes months, not weeks. And without dietary change, muscle alone often can’t overcome ongoing high insulin demand. This is why food and strength work best as partners — food lowers insulin spikes more quickly, while muscle builds lasting metabolic resilience underneath.
Layer 3: Aerobic movement (steady, with harder efforts if appropriate)
Aerobic activity improves insulin sensitivity by increasing glucose uptake during movement and enhancing how efficiently muscles use energy afterward. It also supports cardiovascular health, mitochondrial function, and overall metabolic flexibility.
Brisk walking, cycling, swimming, rowing, or jogging all count — the best option is the one that suits your joints, preferences, and current season of life.
Most evidence shows improvements in insulin resistance with around 150 minutes per week of moderate activity, with additional benefits at higher volumes or intensity where appropriate and sustainable. This doesn’t need to be perfect — consistency matters far more than intensity.
Food: let’s take the fear out of it
One of the biggest myths is: “Insulin resistance means carbs are bad.”
For many women, the bigger issue is refined carbs + frequency + lack of fibre/protein structure.
What usually strains insulin most is:
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eating every 1–2 hours
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refined breakfasts (cereal, toast + jam, pastries, juice)
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carbs on their own, without slowing factors
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late-night eating when the body is tired and less insulin sensitive
So instead of “what do I cut out?”, a more helpful question is:
“How can I make this meal gentler on my insulin?”
That’s where the tools below come in.
Practical, realistic tools
These are not rules. They’re tools — and you get to choose the ones that fit your life, your culture, your budget, and your current capacity.
You don’t need to do all of them to make a difference. Even one or two small shifts can reduce insulin demand and start improving insulin sensitivity — often before anything changes on the scales.
1) Eat in the right order (food sequencing)
This is one of the simplest strategies with a surprisingly big impact.
What it means
When possible, start meals with fibre-rich vegetables, then eat protein and healthy fats, and have starches/sugary foods last.
Why this works
Fibre acts like a “speed bump” in digestion. It slows carbohydrate breakdown and absorption, so glucose enters the bloodstream more gradually and the insulin response tends to be smaller and steadier.
How to do it in real life
No three-course meal required. Think:
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First few bites: salad, vegetables, soup, or a veg-based starter
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Next: protein (tofu/eggs/fish/chicken/beans) + fat (olive oil/avocado/nuts)
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Last: rice, bread, pasta, potatoes, fruit, dessert
Examples
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Stir-fry: veggies/tofu first, then noodles/rice
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Curry: side salad/spinach first, then curry, then rice
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Café brunch: eggs + spinach/mushrooms first, sourdough last
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Taco night: salad/guac + protein first, tortillas/chips last
If this feels too hard
Just do “vegetables first.” Or simply ensure every meal has a visible fibre component.
Common trap
Thinking you must eat the whole meal in strict order. You don’t. Even a gentle shift at the start can change the glucose curve.
2) Move after meals (gently, not as punishment)
This is one of the most underused insulin-sensitivity tools — and it’s free.
What it means
A short period of light movement after eating, ideally within 30–60 minutes.
Why this works
When muscles contract, they take up glucose with much less insulin. Same meal → less insulin “effort.”
What counts (this matters)
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10–15 minute walk
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walking the dog
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dishes + tidying
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hanging washing
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strolling while chatting
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gentle cycling
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dancing to one song
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marching on the spot while you scroll (honestly)
Practical scripts
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“After dinner, I walk while the kettle boils / while the dishwasher runs.”
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“After lunch, I do a 7-minute loop outside.”
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“After breakfast, I do a few chores standing up.”
If you can’t do it after every meal
Choose the meal that tends to hit you hardest — often breakfast or dinner — and start there.
Common trap
Feeling like you need to “burn off” food. You don’t. This is physiology, not punishment.
3) Don’t eat carbs alone (most of the time)
What it means
Pair carbohydrate foods with protein and/or healthy fats and/or fibre when you can.
Why this works
Carbs alone digest quickly → glucose rises faster → insulin response is sharper. Protein/fat/fibre slows digestion and reduces the spike.
Easy pairing swaps
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Toast → eggs / cottage cheese / peanut butter / hummus / avocado
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Crackers → tuna / hummus / cheese / sardines / nut butter
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Fruit → yoghurt / nuts / seeds
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Oats → chia / yoghurt / protein powder / nuts
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Rice → tofu/beans/fish + vegetables
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Pasta → lentils/beans/chicken + olive oil + salad
Helpful mindset
Instead of “I can’t have that,” it becomes: “What can I add to make this gentler?”
Common trap
Thinking you need to remove carbs completely. Many bodies do better with smarter structure, not fear.
4) Rethink breakfast (gently, not dramatically)
Breakfast is a common place insulin strain sneaks in because many standard breakfasts are refined-carb heavy.
What it means
Aim for protein + fibre forward, with carbs included in a supported way.
Why this works
For some people, morning insulin sensitivity is lower. A refined breakfast often creates:
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a big glucose + insulin rise
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then a crash
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then hunger/cravings mid-morning
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then more snacking (more insulin demand)
This doesn’t mean skipping breakfast
It means making breakfast work for you.
Breakfast ideas (mix and match)
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Scrambled eggs/tofu + spinach + tomatoes + feta
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Greek yoghurt + chia + berries + nuts
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Leftovers (often the best): last night’s salmon/chicken/veg
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Smoothie with structure: protein + fibre + fat (not just fruit)
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Beans on toast with eggs/avocado/salad
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Overnight oats with chia + yoghurt + nuts (not just oats + honey)
If you love toast/cereal
You don’t have to ditch it. Try:
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eggs/yoghurt first, toast second
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higher-fibre options
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add nuts/seeds
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add protein on the side
Common trap
Going too extreme, then rebounding. We want sustainable.
5) Use vinegar strategically (optional)
What it means
For some women, vinegar before a higher-carb meal can blunt the glucose rise.
Why it may help
Acetic acid may slow carbohydrate digestion and modestly improve insulin signalling.
How to do it safely
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1–2 tablespoons in a large glass of water
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shortly before the meal
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or use it as part of the meal (salad dressing)
Who should skip this
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reflux/heartburn
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history of ulcers
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swallowing difficulties
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anyone who finds it unpleasant
Important note
This is a “nice to have,” not a core strategy.
6) Choose whole foods most of the time (without perfection)
What it means
Make your default pattern mostly:
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vegetables
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legumes (beans, lentils, chickpeas)
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minimally processed proteins
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whole grains (when you enjoy them)
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nuts, seeds
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fruit
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healthy fats
Evidence summaries commonly find Mediterranean/DASH-style patterns improve insulin sensitivity and metabolic markers.
Why this helps
Highly processed foods tend to:
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digest quickly
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raise glucose faster
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keep insulin elevated longer
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be easy to overeat (engineered for it)
- cause inflammation
Whole foods tend to:
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contain fibre and intact structure
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slow digestion
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reduce insulin demand
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support gut and liver function
A practical “default” plate
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half: vegetables (or salad)
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quarter: protein
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quarter: starch (if desired)
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plus fat (olive oil/avocado/nuts)
Your bread tip - is your bread actually healthy?
There are so many 'high in fiber' or 'with wholegrains' labels out there but don't be fooled
Check the nutrition panel per 100 g:
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Total carbohydrate ÷ fibre
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Aim for ≤ 6 as a rough sign it’s relatively higher fibre and more “whole-food-like”
Not perfect science — but a surprisingly good way to spot products that are mostly refined flour with fibre sprinkled back in.
Common trap
Thinking “whole foods” means cooking from scratch 100% of the time. Not required. Convenience can absolutely fit — we’re just shifting the default direction.
7) Create “insulin rest” windows (spacing meals without grazing)
This is often more powerful than people expect.
What it means
Avoid constant nibbling so insulin can rise and fall rather than stay elevated.
Why it matters
Even small snacks usually trigger insulin. If you’re eating every 1–2 hours, insulin may stay up for long stretches and your metabolism never gets a break.
Gentle, realistic targets
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Try 3 meals with breaks between
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If you snack, make it intentional rather than constant and high protein/fat- think handful of nuts
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Consider a ~12-hour overnight break (e.g., finish dinner 7pm, breakfast 7am) if it suits you
If you’re perimenopausal
Sleep disruption and stress can increase cravings. So we keep it kind: often adding protein earlier makes spacing easier without white-knuckling.
Common trap
Pushing spacing too hard → overeating later. We want “supported spacing,” not deprivation.
8) Add protein and fibre to the meals you already eat (“add, don’t subtract”)
This is often the most sustainable approach.
What it means
Instead of focusing on removing foods, focus on adding:
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protein
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fibre
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healthy fat
to reduce the glucose/insulin impact.
Examples
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Pasta → add lentils/beans + salad + olive oil
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Rice → add tofu/chicken + vegetables
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Sandwich → add tuna/egg + extra salad/veg
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Snack → swap “carbs alone” for “carbs + protein”
This reduces insulin demand without making life miserable.
9) Calm the nervous system (because insulin listens to stress physiology)
What it means
Build small, regular moments of down-regulation.
Why it matters
Stress hormones raise glucose and insulin demand even if food is unchanged. If your nervous system is constantly in “go mode,” metabolism becomes more reactive. Lifestyle evidence summaries include modest benefits from stress-reduction practices.
Practical options
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2-minute breath reset before meals
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short walk outside
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slow down the first five bites
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evening light + digital boundaries
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gentle stretching before bed
This isn’t fluffy. It’s physiology.
10) Make it “easy to win” (consistency beats intensity)
If this starts to feel like a lot, come back to this:
Choose one tool that feels doable this week. Not forever. Just for now.
A “minimum effective dose” might be:
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10 minutes walk after dinner
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protein + fibre breakfast 3 days/week
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clearer meals instead of grazing
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veggies first at dinner
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carbs paired with protein most of the time
When that becomes normal, add another.
Meal timing and intermittent fasting: helpful for some, not for all
Some women do well with time-structured eating. Others feel worse (especially with high stress, poor sleep, history of dieting, or hormonal transition stages where the nervous system is already under strain).
Evidence summaries suggest time-restricted eating can improve insulin sensitivity in certain groups, and intermittent fasting patterns can reduce fasting insulin/HOMA-IR, particularly when weight loss occurs.
If you try any time-structured approach, keep it gentle:
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start with a 12-hour overnight break
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avoid pushing fasting if it worsens sleep, anxiety, binge urges, or migraines
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prioritise protein and fibre so you’re not white-knuckling hunger
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if you’re perimenopausal and sleep is fragile, protect sleep first
Insulin sensitivity isn’t just influenced by what you eat — it’s also shaped by when you eat. This is where chrononutrition comes in. Our bodies run on an internal circadian rhythm that coordinates hormones, digestion, metabolism, and insulin action across the day. Insulin sensitivity naturally follows this rhythm: for most people, it is highest earlier in the day and gradually declines into the evening and overnight.
In practical terms, this means your body is generally better equipped to handle carbohydrates and mixed meals earlier in the day, when insulin works more efficiently and muscles are more responsive to glucose uptake. As the day goes on, insulin secretion tends to rise while insulin sensitivity falls, meaning the same meal eaten late at night often requires more insulin to manage blood sugar than it would in the morning. This isn’t a personal failing — it’s normal human biology.
Chronically eating late, skipping earlier meals, or concentrating most calories at night can push insulin demand higher over time, especially in women already dealing with insulin resistance, stress, or disrupted sleep. Late eating also overlaps with rising melatonin levels, which further reduces insulin effectiveness and can worsen post-meal glucose spikes. Over months and years, this mismatch between food timing and circadian biology can quietly contribute to higher insulin levels and metabolic strain.
The encouraging part is that small shifts in timing can make a meaningful difference. Front-loading protein and energy earlier in the day, eating regular meals, and allowing a longer overnight fasting window all help align food intake with your body’s natural insulin rhythm. Chrononutrition isn’t about rigid rules or early dinners at all costs — it’s about working with your biology, so insulin doesn’t have to work harder than it needs to.
Sleep: the most underestimated insulin tool
If you only improve one “non-food” factor, let it be sleep.
Helpful priorities:
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consistent wake time most days
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morning light exposure
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caffeine cut-off
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evening wind-down routine
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protein at dinner if night waking is hunger-driven
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treat snoring/suspected sleep apnoea seriously (this matters for metabolic health)
Better sleep duration and regular schedules are commonly associated with improved insulin sensitivity in lifestyle summaries.
A quick word on smoking, alcohol, and ultra-processed “insulin noise”
If relevant:
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Smoking cessation can improve insulin sensitivity (even fairly quickly in some mechanistic work).
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Alcohol can worsen sleep, increase appetite dysregulation, and for some women contributes to liver fat and insulin strain. If alcohol is present, a simple experiment (2–4 weeks off) can be very revealing.
What progress can look like (so you don’t lose hope too early)
Early signs you’re moving in the right direction can include:
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steadier energy between meals
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fewer cravings for “quick energy” foods
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less post-meal sleepiness
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easier appetite regulation
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improved mood and sleep consistency
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small shifts in waist measurement
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improved triglycerides/HDL or liver enzymes over time
And sometimes the biggest win is this:
you stop feeling like your body is unpredictable.
A gentle place to start
Instead of asking, “What do I need to cut out?”
Try asking, “What would make my next meal, or my next day, gentler on my insulin?”
Small changes, repeated consistently, are powerful. And your body is far more responsive than you may have been led to believe.
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